Vinnytsia railway station (Ukrainian: Станція Вінниця) is the main railway station in the Ukrainian city of Vinnytsia. It first opened in 1870, and is a part of Southwestern Railways.

According to the "Investment Atlas of Ukraine", the station receives around 1.3 million passengers every year.

The station was built in 1870 as part of a rail line between Kyiv and Podilsk. Initially, the building of the station was made out of wood. A stone building was constructed at the end of the 19th century. In 1940, the current building was constructed. In 1952, it was rebuilt again after being destroyed during the Second World War. The station underwent major renovations in 2003 due to its aging infrastructure.

In 2018, Vinnytsia's railway station was the 6th busiest train station in Ukraine, with 5.7 million passengers.

Major long-distance destinations are: Lviv, Ivano-Frankivsk, Uzhhorod, Chernivtsi, Kyiv, Kharkiv, Dnipro, Zaporizhzhia, Mykolaiv, Kovel, and Odesa.

International destinations include: Budapest, Bratislava, Prague, Bucharest, Chișinău, Minsk, and Moscow.