Kharameh (Persian: خرامه) is a city in the Central District of Kharameh County, Fars province, Iran, serving as capital of both the county and the district. The city is 80 kilometres (50 mi) east of Shiraz, and is surrounded by three lakes: Bakhtegan, Tashk and Maharlu.

At the 2006 National Census, its population was 21,683 in 5,189 households, when it was in the former Korbal District of Shiraz County. The following census in 2011 counted 20,920 people in 5,682 households, by which time the district had been separated from the county in the establishment of Kharameh County. The latest census in 2016 showed a population of 18,477 people in 5,635 households.

There are several tourist places of interest in Kharameh including Bagh-haye Mehrabad (the Mehrabad Gardens), Tangab, 40 Cheshmeh, Doman nim and Ojagh Seyed.

The main occupation of the inhabitants is agriculture with wheat being the largest produced output.